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Tout sur le jus de Grenade
La grenade - un antioxydant puissant

Etudes sur la grenade

Plus de 250 études sur les bienfaits de la Grenade

En voici une partie provenant du livre suivant: La grenade, le fruit aux vertus antioxydantes, anti-inflammatoires, anti-cancer et protectrices du système cardiovasculaire.

ADAMS et al.. Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells. 2006 ; Journal of Agricultural and Food Chemistry 54, 980–985.
AFAQ F.et al.« Pomegranate fruit extract modulates UV-B-mediated phosphorylation of mitogen-activated protein kinases and ac-tivation of nuclear factor kappaB in normal human epidermal keratinocytes paragraph sign. », Photochemistry and Photobiology, 2005 ; 81 : 38–45.
AFAQ F et al.« Anthocyanin- and hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-kappaB pathways and in-hibits skin tumorigenesis in CD-1 mice. », International Journal of Cancer, 2005 ; 113 : 423–433.
AHMED S et al.« Punica granatum L. extract inhib-its IL-1beta-induced expression of matrix metalloproteinases by inhibiting the activation of MAP kinases and NF-kappaB in human chondrocytes in vitro. », Journal of Nutrition, 2005 ; 135 : 2096–2102.
ALBRECHT M. et al., « Pomegranate extracts potently suppress proliferation, xenograft growth, and invasion of human prostate cancer cells. », Journal of Medicinal Food, 2004 ; 7 : 274–283.
AVIRAM M., et al. « Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation. », Clinical Nutrition, 2004 ; 23 : 423–433.
AZADZOI K. M., et al.« Oxidative stress in arteriogenic erectile dysfunction : prophylactic role of antioxidants. », Journal of Urology, 2005 ; 174 : 386–393.
CARDUCCI et al., A phase II study of pomegranate extract for men with rising prostate-specific antigen following primary therapy. – ASCO Genitourinary Cancers Symposium, Prostate Cancer, 2011.
ESMAILLZADEH A., et al.« Cholesterol-lowering effect of concentrated pomegranate juice consumption in type II diabetic patients with hyperlipidemia. », Int. J. Vitam. Nutr. Res., 2006 ; 76, 3 : 147–151.
FISCHER-ZORN A, ARA V, Granatapfelsaft -chemische Zusammensetzung und mögliche Verfälschungen, Flüssiges Obst 08:386-393 (2007)
FOREST C. P et al.« Efficacy and safety of pomegranate juice on improvement of erectile dysfunction in male patients with mild to moderate erectile dysfunction : a randomized, placebo-controlled, double-blind, crossover study. », Int. J. Impot. Res., 2007 ; 14 : Online-Publikation vor Druck.
GIL M. I., et al. « Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. », Journal of Agricultural and Food Chemistry, 2000 ; 48 : 4581–4589.
HAIDARI et al. Pomegranate (Punica granatum) purified polyphenol extract inhibits influenza virus and has a synergistic effect with oseltamivir, University of Texas Health Science Center at Houston, USA, 2009
HARTMAN R. E. et al., « Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer’s disease. », Neurobiol. Dis., 2006 ; 24, 3 : 506–515.
HUANG T. H. et al., « Pomegranate flower improves cardiac lipid metabolism in a diabetic rat model : role of lowering circulating lipids. » British Journal of Pharmacology, 2005 ; 145 : 767–774.
HUANG T.H. et al., « Antidiabetic action of Punica granatum flower extract : activation of PPAR-gamma and identification of an active component. », Toxicology and Applied Pharmacology, 2005 ; 207 : 160-169.
HUANG T. H. et al., « Pomegranate flower extract diminishes cardiac fibrosis in Zucker diabetic fatty rats : modulation of cardiac endothelin-1 and nuclear factor-kappaB path-ways. », Journal of Cardiovascular Pharmacology, 2005 ; 46 : 856-862.
JUNG K.H. et al., « Suppressive effect of Punica granatum on the production of tumor necrosis factor (Tnf) in BV2 microglial cells. » Biological and Pharmaceutical Bulletin, 2006; 29 : 1258–1261.
KHAN N., et al.« Pomegranate fruit extract inhibits prosurvival pathways in human A549 lung carcinoma cells and tumor growth in athymic nude mice. », Carcinogenesis, 2007 ; 28, 1 : 163–173.
KHAN N., AFAQ F., et al.« Oral consumption of pomegranate fruit extract inhibits growth and progression of primary lung tumors in mice. », Cancer Res., 2007 ; 67, 7 : 3475–3482.bibliographie 119
KIM N.D. et al., « Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer. », Breast Cancer Research and Treatment, 2002 ; 71 : 203–217.
KRISTAL et al., One year of pomegranate juice consumption decreases oxidative stress, inflammation, and infections in hemodialysis patients, American Society of Nephrology Meeting, 2010.
KAWAII S., LANSKY E. P., « Differentiation-promoting activity of pomegranate (Punica granatum) fruit extracts in HL-60 human promyelocytic leukemia cells. », Journal of Medicinal Food, 2004 ; 7 : 13–18.
LANSKY E. P., et al.« Pomegranate (Punica granatum) pure chemicals show possible synergistic inhibition of human PC-3 prostate cancer cell invasion across Matrigel. », Investigational New Drugs, 2005 ; 23 : 121–122. (Erratum in : Investigational New Drugs, 2005 ; 23 : 379).
LOREN D. J., et al.« Maternal dietary supplementation with pomegranate juice is neuroprotective in an animal model of neonatal hypoxic-ischemic brain injury. », Pediatric Research, 2005 ; 57 : 858–864.
NAZ S, SIDDIQI R, AHMAD S, et al. Antibacterial activity directed isolation of compounds from Punica granatum. J Food Sci 2007;72:M341
NEURATH A. R., et al.« Punica granatum (Pomegranate) juice pro-vides an HIV-1 entry inhibitor and candidate topical microbicide. », BMC Infect. Dis., Oct. 2004 ; 4 :41.
NEURATH A. R., et al.« Punica granatum (pomegranate) juice pro-vides an HIV-1 entry inhibitor and candidate topical microbicide. », Ann NY Acad. Sci., 2005 ; 1056 : 311–237.
PANTUCK A. J. et al., « Phase II Study of Pomegranate Juice forMen with Rising Prostate-Specific Antigen following Surgery or Radiation for Prostate Cancer. », Clin. Cancer Res., 2006 ; 12, 13 : 4018–4026.
PANTUCK AJ et al.: Long term follow up of phase 2 study of pomegranate juice for men with prostate cancer shows durable prolongation of PSA doubling time. The Journal of Urology (2009) 181(4):295
REDDY M. K., et al.« Antioxidant, Antimalarial and Antimicrobial Activities of Tannin-Rich Fractions, Ellagitannins and Phenolic Acids from Punica granatum L. », Planta Med., 2007 ; Online-Publikation vor Druck.
ROSENBLAT M., et al.« Antioxidative effects of pomegranate juice (PJ) consumption by diabetic patients on serum and on macrophages. », Atherosclerosis, 2006 ; 187, 2 : 363–371.
SEERAM et al. Comparison of antioxidant potency of commonly consumed polyphenol-rich beverages in the United States. J Agric Food Chem. 2008 Feb 27;56(4):1415-22. Epub 2008 Jan 26.
SCHUBERT S. Y et al.« Antioxidant and eicosanoid enzyme inhibition properties of pomegranate seed oil and fermented juice flavonoids. », J. Ethnopharmacol., 1999 ; 66, 1 : 11–17.
SCHUBERT S. Y et al.« A novel mechanism for the inhibition of NF-kappaB activation in vascular endothelial cells by natural antioxidants. », The Federation of American Societies for Experimental Biology Journal, 2002 ; 16 : 1931–1933.
SHIUAN CHEN et al. Pomegranate Ellagitannin–Derived Compounds Exhibit Antiproliferative and Antiaromatase Activity in Breast Cancer Cells In vitro, Cancer Prev Res January 2010 3:108-113.
SHUKLA M., et al.« Consumption of hydrolyzable tannins-rich pomegranate extract suppresses inflammation and joint damage in rheumatoid arthritis. », Nutrition, 2008 May 17.
SHUKLA M., et al.« Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes in vitro. », J. Inflamm., (Lond). Jun. (2008), 5(1):9.
SYED, D.N. et al. . Phytochemopreventive effect of pomegranate fruit extract on UVA-mediated activation of cellular pathways in normal human epidermal keratinocytes. 2006. Photochem Photobiology 82(2): 398-405.


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Les vertus thérapeutiques décrite sur se site, ont été démontrées avec des jus de Grenade extrêmement concentrés. Les jus de Grenade classique ne possèdent à priori pas des effets comparables. Demandez conseil à votre pharmacien ou à votre thérapeute. Nous vous invitons également à télécharger le livre ci-joint.

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